Sand Storm, in combination with ice relocation like Mandatory Seed Replacement and Tenma Line, can effectively act as nisei marker for ending the run. This combo would be able to tax the runner massive amounts of credits on an expensive remote, opening a scoring window.

This card is basically just to tax the runner a bit more, preferably with an expensive piece of ice. If a breaker like Gordian Blade is breaking a DNA Tracker, then it would cost the runner 7 credits. Subtracting the card's rez cost equals a credit advantage of 5 credits in that scenario, better than a Hedge Fund, which gives a 4 credit advantage.

One synergy to mention is Komainu, which does not lose its subs until the run ends.

While the synergy with Komainu is notable, it will never lead to a flatline as the Runner is given the opportunity to jack out after Code Replicator fires. In addition, that means Code Replicator must be pre-rezzed (so that it triggers on-pass) losing a bit of its surprise factor. While this takes away from its ability to be a menacing kill option, it's a very strong taxer as you mentioned. —
However, I'd suggest you compare it to a similar-gameplan upgrade next time rather than Hedge Fund. Comparing Code Replicator to Marcus Batty/Bio Vault/Embolus would be more appropriate. —
You are right. An even better comparison would be Red Herrings. —
I will edit it, eventually —

Lets compare this to Nisei MK II.

Viral Weaponization trashes the runner's grip, taxing them ~5 clicks. It also has the side benefit of disrupting their game plan. Nisei MK II, when used on a scoring server, would cost the runner a click and a massive amount of credits. It can also open a scoring window.

Edit: There are cases where removing the cards in the runner's grip is better than ending the run, such as hurting the runner's tempo or as part of a mill deck.

Amani Senai —
Influence 4 hurts, and it can be prevented due to the trace, not to mention that you need to protect it and the agenda at the same time. The net tax from beating the trace would be ~4, since any more would require you to spend credits. It would only have utility by opening a scoring window if the runner has less credits than you, and you still have to outspend him. —
Nisei MK II does the same without needing Amani Senai. —
Not every gameplan needs a Nisei token over net damage. Any Jinteki deck that wants to grind you out could gladly use this agenda. Combo it with Mental Health Clinic for maximum damage. —
Comparing this to Nisei is kinda pointless cause they do vastly different things in different decks —
Thank you for telling me, I now understand how this agenda is supposed to be used. I will edit my original post. —
Still editing —
The trick is of course that you can play both Nisei MK II and viral weaponization. You also play gene splicer en NGO front for the bluffing potential. —

This card is the one-time program version of Desperado run economy.

Lets compare this card to Jackpot, a card with similar mechanics. At the start of each turn, you would place 1 credit on Jackpot, but can only retrieve them when you steal an agenda, (which may not even occur late in the game). Bankroll places a credit per successful run, and if we consider that as once per turn for an aggressive criminal, is similar to Jackpot in that regard. However, it also costs 1 credit install compared to Jackpot's 0.

Its credits can be pulled at any time, compared to Jackpot's only when an agenda is stolen, but occupies a memory unit in the meantime. However, Jackpot can be trashed if tagged.

In conclusion, its power level is about equal to Jackpot's, and should be considered in aggressive criminal decks with spare MUs.