Clicks are everything, especially to a faction that has a winning amount of 3/2 agendas in their decks. Having that extra 4th click sets up the temporary remote to score those agendas freely from HQ, (save for Clot's interference). Biotic Labor is expensive and is a one-time use, Director Haas needs serious protection to avoid giving the Runner points, and Haas Arcology AI is too awkward to set up and protect, so what alternatives do we have? This Agenda, and a lot of risk taking.
Mandatory Upgrades is a difficult Agenda to score. Although a Mushin No Shin can prep the card for a next-turn score, you'd better hope the single piece of ICE in front of it is good enough protection, or you're a demon with bluffs. Turntable is also salt in the wound if you do manage to score the Upgrades. Losing a potential 4th click and giving the Runner 2 points for the privilege hurts...but maybe that's a good thing.
Data and Destiny brought about the next sleuth of cards to get us thinking of existing card combos, and one important combo is that of Mandatory Upgrades and Media Blitz. Now, with Media Blitz out, the Runner can steal your Mandatory Upgrades and you gain the benefit of the agenda as if you had scored it. With Lily Lockwell's Operation tutor ability, and HB's natural wizardry at fetching cards from Archives, there's a good chance you can recover Media Blitz and get it back online, even the turn after it was removed.
Could you forfeit a 2 point agenda to the Runner if it meant having a re-occurring Biotic Labor that you only have to pay once for? Your server strength and luck will determine its payoff, but Mandatory Media can certainly be a thing!* (Unless Data Dealer becomes the meta.)