This card can give you incredible mileage in Jinteki: Replicating Perfection or Industrial Genomics: Growing Solutions.

Firstly it lets you stack advancement tokens, this means it can be a target for Space Camp and Trick of Light. Inside Weyland it can also benefit from Shipment from Kaguya, Hollywood Renovation or any of the other cheesy Weyland cards that allow/help you advance Ice.

Secondly it lets you use any subroutine, this is great because some of the best ice for these Jinteki decks are Excalibur or Susanoo-No-Mikoto which are both Uniques. Furthermore it can be used to fire net damage subroutines such as Neural Katana or trash a program routines from other Ice like Ichi 1.0, Grim or Swordsman. It also fills in a big gap in Jinteki ice - it can also let you end the run. Remember Wormhole lets you fire off strong subroutines that have the misfortune of sitting on low strength Ice or Ice that don't often get encountered, so don't forget Architect or Crick. An even weirder possibility is to use it to trash hardware by combining it with Taurus or using it to 'refire' failed traps like Whirlpool.

Another benefit of this ice compared to staples such as Komainu is that it is not vulnerable to Parasite.

Strengths: With a full 3 advancement tokens on it (or even just 2) it is not particularly vulnerable to derez abilities such as Emergency Shutdown or Crescentus. Since the surprise factor will likely be low in any case you could also rez it early with Executive Boot Camp against DDoS/Blackmail style decks. It will cost Cyber-Cypher 4 to break, Gordian Blade or Eater 6 to break and Faust a whopping 4 cards as well. It will also stop Endless Hunger in its tracks, since it is not an ETR subroutine... even though you can use it to ETR. For added hilarity you can even land some borrowed brain damage from a lowly Viktor 1.0

Weaknesses: Wormhole can be a Femme Fatale target, it can be broken for 1 counter with D4v1d and it can also be broken with Knight. Once you advance it, it will also be the first piece of ice that gets bounced by Leela Patel: Trained Pragmatist's ability.

The cost could also be considered a weakness, since it costs a combination of 9 or 3 advancement tokens to rez it. It's worth noting that it loses one of the big benefits of Ice by telegraphing itself as an advancable, although it can make up for it in flexibility.

Lastly Wormhole is completely worthless if you don't have any other Ice rezzed, so you will need to support it by playing other Ice with useful subroutines.

Janky Combos: I don't recommend trying for this sort of thing but you could try and combine it with Inazuma, Sensei, Marker, TL;DR, Flare, Shinobi, Bullfrog or even Cell Portal. Marcus Batty is a more reasonable and realistically landable combo which can potentially do some damage as well.

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Spoon makes this ICE very sad. Especially Spoon + D4vid. —
If they land the Spoon in the same turn yes I will not get much out of it, but usually I will use Trick of Light to fast advance with the advancement counters after rezzing (or before rezzing, never waste a chance to score!). In IG I've got Museum of History it so that we may be reunited once again. Multiple Hostile Infrastructures make ice destruction very sad. Sadly D4v1d is a fact of life that can only be dealt with by wearing down its counters or program destruction. —

Reuse is a very limited card, but there is one deck that can make use of it in the normal course of play: Industrial Genomics: Growing Solutions

Instead of needing to draw up above 5 in order to shed a few cards, you can spend 2 to fill your archives with face-down cards and gain s at the same time. This can be a great way to recover from getting Account Siphoned or Vamped or even needing to rez a lot of ice or assets (such as Hostile Infrastructure) during the previous turn. It is also useful just to 'reload' archives if the runner has just accessed them the previous turn as well. Lastly it can be a powerful response to Fisk Investment Seminar.

Now in a lot of ways this card could be compared unfavourably with Celebrity Gift, which is in faction and doesn't involve discarding cards but lets make a direct comparison here:

Reuse has a cost of 0 vs Celebrity Gift's cost of 3

On a hand of 5 cards + 1 mandatory draw Reuse will gain a maximum of 10 and Celebrity Gift will gain a maximum of 7 - as the number of cards in hand decreases Reuse becomes more efficient than Celebrity Gift. As the number of cards in hand go above 5 Reuse is also potentially even more profitable

Both Reuse and Celebrity Gift are double type operations and cost 2

Celebrity Gift gives away information which can be very double sided for Jinteki, intimidation and mind games is a potential benefit, giving away warnings to your opponent regarding your potential traps and tricks (as well as the presence of Agendas) may be a disadvantage.

Reuse costs you cards, which represent a each to draw (or replace, after you trash them with this ability) so mechanically it gets you 2 per . Under ordinary circumstances this is not an acceptable return from a card that costs a to draw and 2s to play. This is why you can only make good use of it in Industrial Genomics Decks, where you want to trash cards anyway and it can potentially make what is normally an inefficient set of actions (drawing just to discard into archives) into a profitable bonus.

Support cards and potential janky combos? In Industrial Genomics you will want to run Jackson Howard, Crick and Museum of History anyway to enable long term use of your Id ability. Other potential recursion cards such as Allele Repression, Archived Memories, Architect, Team Sponsorship or even Reclamation Order are possible too. The only other potential use for this card is in Cerebral Imaging: Infinite Frontiers as a way of making a lot of s very quickly (maybe after getting vamped for everything the previous turn or to fund a mega Midseason Replacements (but that will use up 3s).

Alternative cards for Industrial Genenomics include: Heritage Committee, Green Level Clearance or Blue Level Clearance which package draw with some additional benefit.

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To be honest, I've only ever seen this card in Cerebral Imaging. 2 credits per card is just not a good enough deal in Industrial Genomics, which has access to carsds like Celebrity Gift, Turtlebacks and Diversified Portfolio (as well as tending not to need much money). Meanwhile, Cerebral Imaging combo decks can discard every card that isn't in the combo to potentially gain far more than 10 credits. —
Cerebral Imaging's power shutdown combo? Draw all into hand, reuse everything but Jackson and accelerated diagnostics, then install jackson, use him and play accelerated diagnostics. —