As of late 2020, Adjusted Matrix is useful almost exclusively with Deus X. Which allow you to make any ice behave basically like a Bioroid (click to break). Unless Sandburg or Helheim Server is used, this will allow you to break any ices at the cost of clicks. Against high strength ices, it is a bargain. All this at the cost of 8 credits (still expensive).

Otherwise, with any other breaker, it allow you to interact with any ice on the board. Houdini and Engolo are very good for this. With that, you can still use only one breaker to break anything. It won't help much against Glacier, but it will help in a pinch. And it doesn't take any MU.

With it's high cost of 5 credits, it won't see much use. But with a cost of 2 influences, it can be used in any factions.

Note the flavor text, it describe exactly what the card does, all with a pretty image. Good design.

Probably best with Endless Hunger as it has base 11 strength and can handle etrs. Apex with this and E3 has a way to walk through servers, albeit without the threat of Apocalypse.

Outside of that, I can only see Shapers using this right now. It does let you have a decent AI in stealth with either Houdini or Switchblade as great targets depending on the match up. Torch, Cybercypher, and Study Guide are also worth mentioning, but be careful not to spend too much on your setup. After all, this does only let you click through things...